Pharmaceutical transition to non-CFC pressurized metered dose inhalers
نویسندگان
چکیده
منابع مشابه
Optimizing aerosol delivery by pressurized metered-dose inhalers.
The modern era of aerosol therapy began with the introduction of the Medihaler Epi in 1956, after a 13-year-old asthmatic told her father, an officer in the Riker company, that asthma medications should be as convenient to use as hair spray and she complained that the bulb atomizer leaked in her school bag. Since then, advances in technology have made aerosol delivery much more efficient, so th...
متن کاملPressurized metered dose inhalers and add-on devices.
Metered dose inhalers (MDIs) which have a valve holding chamber plus a mouthpiece or mask have, in recent years, markedly improved the ease, speed and reliability of aerosol therapy for reversible airflow obstruction in adults, children and infants. MDIs, effective and easily accessible when patients are away from home, are the gold standard for the treatment of reversible airflow obstruction s...
متن کاملComparison of the safety of drug delivery via HFA- and CFC-metered dose inhalers in CAO.
The objective of this study was to compare the long-term safety of a fixed combination of fenoterol hydrobromide (50 microg) and ipratropium bromide (20 microg) delivered using a metered dose inhaler (MDI) formulated with a non-chlorinated propellant, hydrofluoroalkanel34a (HFA-MDI), with delivery using the conventional chlorofluorocarbon propellant (CFC-MDI, Berodual/Bronchodual). The study wa...
متن کاملPredictors of correct technique in patients using pressurized metered dose inhalers
BACKGROUND Corret inhaler technique is recommended by guidelines for optimum asthma care. The objective of the study is to determine real life predictors of correct pressurized metered dose inhaler (pMDI) technique in Asthma and COPD patients. METHODS Two hundred eight adult patients aged 18+ from respiratory outpatients (69.2%) and the community on regular pMDI for a diagnosis of Asthma (...
متن کاملReview: pressurized metered-dose inhalers are as effective as other handheld inhalers for corticosteroid use in asthma.
D a t a s o u r c e s Studies published from 1966 to July 1999 were identified by searching the Cochrane Airways Group trials database (derived from MEDLINE, EMBASE/Excerpta Medica, CINAHL; hand searches of 18 relevant journals and proceedings of 3 respiratory societies; and reviews of bibliographies of relevant studies). Pharmaceutical companies that manufacture inhaled asthma drugs were conta...
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ژورنال
عنوان ژورنال: Respiratory Medicine
سال: 2000
ISSN: 0954-6111
DOI: 10.1016/s0954-6111(00)80143-2